Clinicopathological Characteristics of Low to Intermediate Grade Neuroendocrine Tumors with Oncocytic Features

Neuroendocrine tumors (NETs) with oncocytic features are rare. To date, few studies have described the metastatic characteristics of these tumors, most which were limited by low number cases. One article characterized intermediate to high grade (G2 and G3) NETs pancreas as having an ominous outcome; however, low-grade have, our knowledge, been hitherto unexplored. Our study clinicopathological 32 intermediate-grade various organs. The frequent site was liver (63%). rate cases compared Riihimaki’s (metastatic G1/G2 reported), well Heetfeld’s Lithgow’s G3 reported). overall is 84.4%, significantly higher than that G1/2 from (84.4% vs. 25%, p < 0.0001), while similar 86.5%, > 0.05) 80.8%, 0.05). These data indicate could potentially be high-risk in addition Ki-67 index, mitotic count, necrosis. Thus, imaging such magnetic resonance (MRI) may warranted detect metastases distinctive cytologic even absence other features.